Incidence of accidental skin burns are increasing across the globe. Life threatening skin injuries, traumas, and burns require immediate surgical procedure to restore skin and avoid future complications. Skin burns are broadly classified into three levels, namely 1st, 2nd, and 3rd degree burns. In third degree of burns where there is little or no intact skin, artificial skin graft is the most useful treatment option. Artificial skin covers and protects the wound and also promotes regeneration of natural skin.
Artificial skin is usually prepared from collagen, which is easily resorbed by the body and facilitates generation of new skin on the affected area. According to the American Burn Association, 486,000 people received medical treatment for minor burns and 70,000 people were hospitalized for severe skin burn requiring acute care in the U.S, in 2015. Various players in the market are carrying R&D activities to develop new technology related to artificial skin regeneration. One such instance is an autologous spray on skin, Recell, by Avita Medical.
Artificial Skin Treatments
Various skin repair devices are available, which are used to heal the affected part. These include Dermagraft, OrCel, Integra, Biobrane, Apligraft, Matriderm, Hyalomatrix, Renoskin, and Composite Cultured Skin. Dermagraft is used to help in wound closure of diabetic foot ulcers. Orcel is used to cover and aid in wound healing. Composite Cultured Skin also contains living cells and is specifically used in children with recessive dystrophic epidermolysis bullosa. Integra is used for treatment of severe burns.
On the basis of material type, the regenerative artificial skin market is segmented into temporary skin material, permanent skin material, and composite skin material.
Temporary skin material: Its effect lasts between several months and 2.5 years, depending on the type, quality, and quantity of injected material.
Permanent skin material: These are epidermal skin and dermal skin materials. Bio-Alcamid is a synthetic polymer that contains 97% water. It is injected into the inner tissue to fill and thicken it.
Composite Skin Material: These are further sub-segmented into skin graft and engineered skin material.
Some of the key players in the global regenerative artificial skin market are Integra Life Sciences Corporation, Mylan N.V., Johnson & Johnson Services, Inc. Smith & Nephew and Mallinckrodt plc.
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