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Chennai’s Rainbow Children’s Hospital successfully undergoes bone marrow transplant for rare genetic condition

The first and youngest child in India to survive ECMO after undergoing bone marrow transplantation for a rare disease

Doctors at Rainbow Children’s Hospital in Chennai gave a new lease of life to a baby who underwent a bone marrow transplant for a rare genetic condition known as monogenic inflammatory bowel disease. The boy was put on extracorporeal membrane oxygenation (ECMO) support post the complications of BMT. It is the first case in India where ECMO CPR was performed on a child who underwent a bone marrow transplant and the first child to survive ECMO following the bone marrow transplant.

Dr R Karthik Narayanan, Senior Consultant Pediatric Intensive Care, Rainbow Children’s hospital said, “It’s not only important that we save a baby which would have lost his life with 99 per cent probability, but true success is to ensure that the baby has a satisfactory neurological outcome so that, he can regain lost milestones of development and lead a normal life. Also, another important aspect in this child was to ensure the success of transplanted bone marrow. We at Rainbow Children’s hospital followed the baby for over a year. The team made scheduled follow up visits ensuring rehabilitative care which included physiotherapy, antibiotic and antiviral prophylaxis, tracheostomy care and post-decannulation care.”

Sarvanakumar Rajan, Unit Head, Rainbow Children’s hospital, said, “This clinical case is first in many aspects. In the world, only eight children who underwent bone marrow transplants to date have been offered ECMO (all in USA and UK) according to the ELSO registry (an international registry for outcomes of patients on ECMO). No child has survived post-BMT after ECMO while he had a multi-organ failure due to severe infection and sepsis. We are glad that Rainbow Hospital was able to treat Lochen and be a part of history.”

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