Mucormycosis is a fungal disease, that usually occurs in patients with a compromised immune status
Global Hospitals, Parel has formed a Multidisciplinary Team (MDT) consisting of ENT, infectious diseases specialist, critical care, physician, and endocrinologist, who would jointly treat mucormycosis patients. The hospital has launched Mumbai’s first mucormycosis clinic, to offer comprehensive and planned care for the patients.
Mucorales is the largest and best-studied order of zygomycete fungi, which are sometimes called pin moulds. This rare fungal infection destroys bone, invades blood vessels. It spreads aggressively from the nose to palate to the orbits and the brain. The low immunity caused by the COVID-19 infection, along with diabetes mellitus made Shaila Sonar, from Dhule, interior Maharashtra, more susceptible to the rare and serious fungal infection, mucormycosis. The infection was so aggressive, that even after four surgeries performed outside Global Hospital, it continued to persist. This led to the patient’s eventual consultation on December 1, 2020. Surgery along with appropriate anti-fungal therapy followed. Sonar was operated on and half of her palate was removed in the process of clearing the fungal infection. Her eyes were saved due to timely and precise surgical intervention. Post-operation, she underwent anti-fungal therapy and rehabilitation. 21 days after her admission, she was discharged.
Dr Milind Navalakhe, ENT Surgeon, Global Hospitals, Parel said, “Mucormycosis is a fungal disease, that usually occurs in patients with a compromised immune status. I have treated a substantial number of diabetic patients with this fungal infection, even before the COVID era. In the early 90s, only one to two patients would visit me for treatment of this infection. But in the last 25 years, per year 25-30 patients received treatment for it. Now, within one to three months of post-COVID recovery, around 50 low-immunity patients, with diabetes and on steroids, got this fungal infection.”
Dr Navalakhe added, “Unfortunately, it does not cause significantly different symptoms than a cold or nasal block. Initially, blackish discolouration on the inside of the nose and palate is seen. Hence, it goes unnoticed to an advanced stage. By the time the patients seek medical attention, it is already in the advanced stage called sinonasal mucormycosis. It mainly starts in the nasal cavity or paranasal sinuses, involving the nose. It then becomes rhino-orbital, wherein the eyes are involved. Eventually, it becomes rhino-cerebral, with the involvement of the brain. Many patients realise the need for medical intervention when there is palatal involvement. This harmful disease usually starts in the sinuses and then proceeds to the eyeball, the palate, and the brain, destroying the structure. This infection kills tissues causing necrosis. Treatment requires the removal of dead tissues and even the tissues surrounding it, to curb the spread of the infection.”
“Early diagnosis is imperative to start treatment early. Early debridement produces optimal results and prevents morbidity and mortality. It is also necessary to get diabetes under control to reduce the chances of infection. To prevent the devastation caused by the infection, be alert and seek immediate treatment. Our newly launched clinic, will be a boon for the patients by diagnosing and treating them, ultimately helping to improve their quality of life,” said Dr Vasant Nagvekar, HOD – Infectious diseases, Global Hospital, Parel.
“As COVID compromises the immune system, fungal infections easily afflict elderly patients and those with comorbidities. We have set up a Multidisciplinary team to cull the infection at the root, by managing pre-existing conditions like diabetes. The MDT will conduct an all-round evaluation of the patient, taking timely steps to prevent the spread of the infection. The team of experts is also well-equipped to handle any complications and advanced cases of invasive fungal infections,” concluded Dr Vivek Talaulikar, CEO-Global Hospitals, Mumbai.