Manipal Hospitals treats giant cell tumour on 85-year-old

The tumour was measuring approximately 6X8 cm in size and had destroyed the crucial weight-bearing zone of the femur bone

Manipal Hospitals, Old Airport Road successfully removed a benign aggressive bone tumour called giant cell tumour around the knee in an independently living 85-year-old woman, the first recorded case of its kind at this age in India. 


Rajambal from Salem was referred to Dr Srimanth BS, Consultant – Orthopaedic Onco Surgery, Manipal Hospitals, Old Airport Road after facing severe pain and swelling in her left knee for three to four months. The team were suspecting a cancerous growth or bone metastases at her age, but a series of tests including a minimally invasive biopsy procedure indicated a giant cell tumour of the lower part of her thigh bone around her knee region (lower end femur). This tumour was measuring approximately 6X8 cm in size and had destroyed the crucial weight-bearing zone of the femur bone.

Dr Srimanth BS and his team did further tests to confirm the diagnosis since it was extremely rare at this age and immediately consulted Rajambal and her relatives about the necessity of a tumour removal surgery for her knee.

Dr Srimanth BS states, “Considering her age, age-related arthritis and extent of bone destruction by the tumour, we would advise removal of the diseased lower part of the femur and replace it with a Modular Tumor Megaprosthesis. But Rajambal surprisingly had minimal osteoarthritic changes around the knee, coupled with her motivation and enthusiasm she instead consented to Extended Curettage and reconstruction procedure which would help adequately clear the tumour and also retain her native knee joint. Her age, diabetes and hypertension also placed her at high risk. With help of our anaesthesia team, endocrinologist, cardiologist and rehabilitation team, the treatment was successful and she could walk the very next day. We have been consulting the patient for one-year post the surgery, she is free from a tumour and her quality of life (independently living) has enhanced exponentially.”

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